1 to 10 of 27 literature results

• Use of diaminofluoresceins to detect and measure nitric oxide in low level generating human immune cells.

  Nitric oxide ((*)NO) has been implicated in multiple physiological and pathological immune processes. Different methods have been developed to detect …

  Authors: Adriana Tiscornia, Ernesto Cairoli, Maria Marquez, Ana Denicola, Otto Pritsch, Alfonso Cayota

  Source: Journal of immunological methods. 2009 Mar 15

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• Acceleration of nitric oxide autoxidation and nitrosation by membranes.

  The reaction between nitric oxide ((.)NO) and oxygen yields reactive species capable of oxidizing and nitrosating proteins, as well as deaminating DNA…

  Authors: Matias N Möller, Qian Li, Jack R Lancaster, Ana Denicola

  Source: IUBMB life. 2007 Apr-May

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• Red blood cells in the metabolism of nitric oxide-derived peroxynitrite.

  In this review we have analyzed the reactions of nitric oxide (.NO) with superoxide radical (O(2).-) at the vascular compartment which results in limi…

  Authors: Natalia Romero, Ana Denicola, Rafael Radi

  Source: IUBMB life. 2006 Oct

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• Inactivation of cystathionine beta-synthase with peroxynitrite.

  Cystathionine beta-synthase (CBS) is a homocysteine metabolizing enzyme that contains pyridoxal phosphate (PLP) and a six-coordinate heme cofactor of …

  Authors: Laura Celano, Magdalena Gil, Sebastián Carballal, Rosario Durán, Ana Denicola, Ruma Banerjee, Beatriz Alvarez

  Source: Archives of biochemistry and biophysics. 2009 Nov

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• Membrane "lens" effect: focusing the formation of reactive nitrogen oxides from the *NO/O2 reaction.

  It was previously observed that lipid membranes accelerate *NO disappearance (Liu et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 2175), and here, we …

  Authors: Matias N Möller, Qian Li, Dario A Vitturi, John M Robinson, Jack R Lancaster, Ana Denicola

  Source: Chemical research in toxicology. 2007 Apr

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• The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

  Peroxiredoxin 2 (Prx2) is a 2-Cys peroxiredoxin extremely abundant in the erythrocyte. The peroxidase activity was studied in a steady-state approach …

  Authors: Bruno Manta, Martín Hugo, Cecilia Ortiz, Gerardo Ferrer-Sueta, Madia Trujillo, Ana Denicola

  Source: Archives of biochemistry and biophysics. 2009 Apr 15

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• Peroxynitrite and drug-dependent toxicity.

  Peroxynitrite is the product of the diffusion-controlled termination reaction between two radicals, nitric oxide and superoxide and is a strong oxidan…

  Authors: Ana Denicola, Rafael Radi

  Source: Toxicology. 2005 Mar 15

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• Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets.

  In the search for new therapeutic tools against American Trypanosomiasis palladium complexes with bioactive nitrofuran-containing thiosemicarbazones a…

  Authors: Lucía Otero, Marisol Vieites, Lucía Boiani, Ana Denicola, Carolina Rigol, Lucía Opazo, Claudio Olea-Azar, Juan Diego Maya, Antonio Morello, R Luise Krauth-Siegel,…

  Source: Journal of medicinal chemistry. 2006 Jun 1

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• 2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.

  Three series of benzimidazole N-oxide derivatives were developed and were examined for their activity against trypanosomatid parasites (Trypanosoma cr…

  Authors: Mariana Boiani, Lucía Boiani, Ana Denicola, Susana Torres de Ortiz, Elva Serna, Ninfa Vera de Bilbao, Luis Sanabria, Gloria Yaluff, Héctor Nakayama, Antonieta Rojas de Arias,…

  Source: Journal of medicinal chemistry. 2006 Jun 1

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• The trypanothione-thiol system in Trypanosoma cruzi as a key antioxidant mechanism against peroxynitrite-mediated cytotoxicity.

  Peroxynitrite, the reaction product between superoxide (O(*2)) and nitric oxide (*NO), is a powerful oxidizing species that contributes to macrophage …

  Authors: Leonor Thomson, Ana Denicola, Rafael Radi

  Source: Archives of biochemistry and biophysics. 2003 Apr 1

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