See also "A Soni"
AKT1 BCL2 BCL2L1 breast cancer carcinoid carcinoid tumor CCND1 cell growth cell lines cell proliferation EIF4E ERBB2 MTOR neuroendocrine tumors octreotide phosphatidylinositol-3-kinase phosphorylated phosphorylation progesterone rapamycin somatostatin Thor tumor
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Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors.
The mammalian target of rapamycin (mTOR) signaling pathway has emerged as a promising target for cancer therapy. Rapamycin inhibits mTOR activity but …
Authors: Amy Moreno, Argun Akcakanat, Mark F Munsell, Alpana Soni, James C Yao, Funda Meric-Bernstam
Source: Endocrine-related cancer. 2008 Mar
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eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling.
Activation of translation initiation is essential for the malignant phenotype and is emerging as a potential therapeutic target. Translation is regula…
Authors: Alpana Soni, Argun Akcakanat, Gopal Singh, David Luyimbazi, Yuhuan Zheng, Doyil Kim, Ana Gonzalez-Angulo, Funda Meric-Bernstam
Source: Molecular cancer therapeutics. 2008 Jul
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