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10 literature results
Integrins are the major adhesion receptors of leukocytes and platelets. Beta1 and beta2 integrin function on leukocytes is crucial for a successful im…
Authors: Lena Svensson, Kimberley Howarth, Alison McDowall, Irene Patzak, Rachel Evans, Siegfried Ussar, Markus Moser, Ayse Metin, Mike Fried, Ian Tomlinson,…
Source: Nature medicine. 2009 Mar
View Free Full TextA successful immune response depends on the capacity of immune cells to travel from one location in the body to another--these cells are rapid migrato…
Authors: Rachel Evans, Irene Patzak, Lena Svensson, Katia De Filippo, Kristian Jones, Alison McDowall, Nancy Hogg
Source: Journal of cell science. 2009 Jan 15
View Full TextShedding of adhesion molecules has been described for members of the selectin and immunoglobulin superfamilies, but integrins are not known to be shed…
Authors: Betsy J Evans, Alison McDowall, Peter C Taylor, Nancy Hogg, Dorian O Haskard, R Clive Landis
Source: Blood. 2006 May 1
View Full TextA successful immune response depends on the migration of lymphocytes into lymph nodes or inflamed tissues where they make contact with antigen-present…
Authors: Andrew Smith, Paula Stanley, Kristian Jones, Lena Svensson, Alison McDowall, Nancy Hogg
Source: Immunological reviews. 2007 Aug
View Full TextCD40 is a 48-kDa phosphorylated transmembrane glycoprotein belonging to the TNF receptor superfamily. CD40 has been demonstrated on a range of cell ty…
Authors: David P Inwald, Alison McDowall, Mark J Peters, Robin E Callard, Nigel J Klein
Source: Circulation research. 2003 May 16
View Full TextT cells use integrins in essentially all of their functions. They use integrins to migrate in and out of lymph nodes and, following infection, to migr…
Authors: Nancy Hogg, Melanie Laschinger, Katherine Giles, Alison McDowall
Source: Journal of cell science. 2003 Dec 1
View Full TextUnderstanding how the integrins on leukocytes operate is important because these receptors control the activity of leukocytes in all phases of their l…
Authors: Nancy Hogg, Robert Henderson, Birgit Leitinger, Alison McDowall, Joanna Porter, Paula Stanley
Source: Immunological reviews. 2002 Aug
View Full TextThe T lymphocyte (or T cell) has classically been perceived to be a passive circular cell attaching to other cells or fibrils of the extracellular mat…
Authors: Nancy Hogg, Andrew Smith, Alison McDowall, Katherine Giles, Paula Stanley, Melanie Laschinger, Robert Henderson
Source: Immunology letters. 2004 Mar 29
View Full TextT lymphocytes use LFA-1 to migrate into lymph nodes and inflammatory sites. To investigate the mechanisms regulating this migration, we utilize mAbs s…
Authors: Paula Stanley, Andrew Smith, Alison McDowall, Alastair Nicol, Daniel Zicha, Nancy Hogg
Source: The EMBO journal. 2008 Jan 9
View Free Full TextThe adhesion receptors known as integrins perform key functions for hematopoietic cells. The platelet integrin alphaIIbbeta3 is critical in hemostasis…
Authors: Alison McDowall, David Inwald, Birgit Leitinger, Alison Jones, Ri Liesner, Nigel Klein, Nancy Hogg
Source: The Journal of clinical investigation. 2003 Jan
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