1 to 10 of 22 literature results

• Levels of complexity in pathogen recognition by C-type lectins.

  In pathogen recognition by C-type lectins, several levels of complexity can be distinguished; these might modulate the immune response in different wa…

  Authors: Alessandra Cambi, Carl G Figdor

  Source: Current opinion in immunology. 2005 Aug

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• Sweet talk": closing in on C type lectin signaling.

  C type lectins recognize pathogens by binding to pathogen-specific carbohydrate residues. The finding reported by Rogers et al. (2005) in this issue o…

  Authors: Friederike Meyer-Wentrup, Alessandra Cambi, Gosse J Adema, Carl G Figdor

  Source: Immunity. 2005 Apr

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• Dual function of C-type lectin-like receptors in the immune system.

  Carbohydrate-binding C-type lectin and lectin-like receptors play an important role in the immune system. The large family can be subdivided into subt…

  Authors: Alessandra Cambi, Carl G Figdor

  Source: Current opinion in cell biology. 2003 Oct

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• The C-type lectin DC-SIGN internalizes soluble antigens and HIV-1 virions via a clathrin-dependent mechanism.

  Dendritic cells (DC), professional Ag-presenting cells located in mucosae and lymphoid organs, operate at the interface of innate and adaptive immunit…

  Authors: Alessandra Cambi, Inge Beeren, Ben Joosten, Jack A Fransen, Carl G Figdor

  Source: European journal of immunology. 2009 Jul

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• Ligand-conjugated quantum dots monitor antigen uptake and processing by dendritic cells.

  The dendritic cell (DC) specific pathogen-uptake receptor (DC-SIGN) internalizes antigens for degradation and presentation onto MHC molecules. At the …

  Authors: Alessandra Cambi, Diane S Lidke, Donna J Arndt-Jovin, Carl G Figdor, Thomas M Jovin

  Source: Nano letters. 2007 Apr

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• How C-type lectins detect pathogens.

  Glycosylation of proteins has proven extremely important in a variety of cellular processes, including enzyme trafficking, tissue homing and immune fu…

  Authors: Alessandra Cambi, Marjolein Koopman, Carl G Figdor

  Source: Cellular microbiology. 2005 Apr

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• DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production.

  C-type lectin receptors (CLRs) expressed on APCs play a pivotal role in the immune system as pattern-recognition and antigen-uptake receptors. In addi…

  Authors: Friederike Meyer-Wentrup, Alessandra Cambi, Ben Joosten, Maaike W Looman, I Jolanda M de Vries, Carl G Figdor, Gosse J Adema

  Source: Journal of leukocyte biology. 2009 Mar

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• Distinct kinetic and mechanical properties govern ALCAM-mediated interactions as shown by single-molecule force spectroscopy.

  The activated leukocyte cell adhesion molecule (ALCAM) mediates dynamic homotypic and heterotypic cellular interactions. Whereas homotypic ALCAM-ALCAM…

  Authors: Joost Te Riet, Aukje W Zimmerman, Alessandra Cambi, Ben Joosten, Sylvia Speller, Ruurd Torensma, Frank N van Leeuwen, Carl G Figdor, Frank de Lange

  Source: Journal of cell science. 2007 Nov 15

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• Organization of the integrin LFA-1 in nanoclusters regulates its activity.

  The beta2-integrin LFA-1 facilitates extravasation of monocytes (MOs) into the underlying tissues, where MOs can differentiate into dendritic cells (D…

  Authors: Alessandra Cambi, Ben Joosten, Marjolein Koopman, Frank de Lange, Inge Beeren, Ruurd Torensma, Jack A Fransen, Maria Garcia-Parajó, Frank N van Leeuwen, Carl G Figdor

  Source: Molecular biology of the cell. 2006 Oct

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• Modulation of Toll-like receptor 2 (TLR2) and TLR4 responses by Aspergillus fumigatus.

  Toll-like receptor (TLR)-based signaling pathways in the host may be modulated by pathogens during the course of infection. We describe a novel immuno…

  Authors: Louis Y A Chai, Bart Jan Kullberg, Alieke G Vonk, Adilia Warris, Alessandra Cambi, Jean-Paul Latgé, Leo A B Joosten, Jos W M van der Meer, Mihai G Netea

  Source: Infection and immunity. 2009 May

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