1 to 6 of 6 literature results

• EBV LMP-2A employs a novel mechanism to transactivate the HERV-K18 superantigen through its ITAM.

  EBV encodes latent membrane protein (LMP)-2A that functions as a homologue of the activated BCR. We have previously shown that LMP-2A transactivates a…

  Authors: Francis C Hsiao, Albert K Tai, Agnes Deglon, Natalie Sutkowski, Richard Longnecker, Brigitte T Huber

  Source: Virology. 2009 Mar 1

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• Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity.

  The control of glucose metabolism is a complex process, and dysregulation at any level can cause impaired glucose tolerance and insulin resistance. Th…

  Authors: Olga V Danilova, Albert K Tai, Deanna A Mele, Martin Beinborn, Andrew B Leiter, Andrew S Greenberg, James W Perfield, Jason Defuria, Praful S Singru, Ronald M Lechan,…

  Source: Endocrinology. 2009 Dec

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• Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death.

  Defective signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) is responsible for the human X-linked lymphoproliferative syndrome.…

  Authors: Gang Chen, Albert K Tai, Miao Lin, Francesca Chang, Cox Terhorst, Brigitte T Huber

  Source: European journal of immunology. 2007 Mar

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• HHV-6A infection induces expression of HERV-K18-encoded superantigen.

  BACKGROUND: The human endogenous retrovirus K-18 (HERV-K18) encodes a superantigen that causes deregulation of the immune system. This provirus is tra…

  Authors: Albert K Tai, Janos Luka, Dharam Ablashi, Brigitte T Huber

  Source: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 2009 Sep

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• Murine Vbeta3+ and Vbeta7+ T cell subsets are specific targets for the HERV-K18 Env superantigen.

  Superantigens are a class of proteins that are derived from microorganisms and have the unique characteristic of stimulating T cells in a TCR Vbeta-sp…

  Authors: Albert K Tai, Miao Lin, Francesca Chang, Gang Chen, Francis Hsiao, Natalie Sutkowski, Brigitte T Huber

  Source: Journal of immunology (Baltimore, Md. : 1950). 2006 Sep 1

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• Signaling lymphocyte activation molecule-associated protein is a negative regulator of the CD8 T cell response in mice.

  The primary manifestation of X-linked lymphoproliferative syndrome, caused by a dysfunctional adapter protein, signaling lymphocyte activation molecul…

  Authors: Gang Chen, Albert K Tai, Miao Lin, Francesca Chang, Cox Terhorst, Brigitte T Huber

  Source: Journal of immunology (Baltimore, Md. : 1950). 2005 Aug 15

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