1 to 8 of 8 literature results

• Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease.

  Microglia are the immune cells of the brain. Here we show a massive infiltration of highly ramified and elongated microglia within the core of amyloid…

  Authors: Alain R Simard, Denis Soulet, Genevieve Gowing, Jean-Pierre Julien, Serge Rivest

  Source: Neuron. 2006 Feb 16

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• Role of inflammation in the neurobiology of stem cells.

  Unlike most organs, tissue regeneration and repair are not very efficient in the CNS, which explains the severity of neurodegenerative diseases. Many …

  Authors: Alain R Simard, Serge Rivest

  Source: Neuroreport. 2004 Oct 25

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• Calcineurin and skeletal muscle growth.

  Authors: Shannon E Dunn, Alain R Simard, Renée A Prud'homme, Robin N Michel

  Source: Nature cell biology. 2002 Mar

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• Do pathogen exposure and innate immunity cause brain diseases?

  It had long been thought that the central nervous system was isolated from the immune system owing to the blood-brain barrier and that this organ was …

  Authors: Alain R Simard, Serge Rivest

  Source: Neurological research. 2005 Oct

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• Neuroprotective effects of resident microglia following acute brain injury.

  Microglia quickly react to various neurodegenerative processes by producing cytokines and eliminating cellular debris via phagocytosis. These events a…

  Authors: Alain R Simard, Serge Rivest

  Source: The Journal of comparative neurology. 2007 Oct 20

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• Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia.

  Pluripotent stem cells can differentiate into a variety of cell types during tissue development and regeneration. However, it is still unclear whether…

  Authors: Alain R Simard, Serge Rivest

  Source: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2004 Jun

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• Bone marrow stem cells to the rescue of Alzheimer's disease

  Authors: Alain R Simard, Serge Rivest

  Source: Médecine sciences : M/S. 2006 Oct

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• Alterations in slow-twitch muscle phenotype in transgenic mice overexpressing the Ca2+ buffering protein parvalbumin.

  The purpose of this study was to determine whether induced expression of the Ca2+ buffering protein parvalbumin (PV) in slow-twitch fibres would lead …

  Authors: Eva R Chin, Robert W Grange, Francois Viau, Alain R Simard, Caroline Humphries, John Shelton, Rhonda Bassel-Duby, R Sanders Williams, Robin N Michel

  Source: The Journal of physiology. 2003 Mar 1

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