1 to 10 of 18 literature results

• Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum.

  The origin of all mitochondria can be traced to the symbiotic arrangement that resulted in the emergence of eukaryotes in a world that was exclusively…

  Authors: Heather J Painter, Joanne M Morrisey, Michael W Mather, Akhil B Vaidya

  Source: Nature. 2007 Mar 1

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• Mitochondrial evolution and functions in malaria parasites.

  Mitochondria in malaria parasites have some unusual evolutionary and functional features. The drastic reduction in the size of their mitochondrial gen…

  Authors: Akhil B Vaidya, Michael W Mather

  Source: Annual review of microbiology. 2009

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• Complex inheritance of the plasmodial surface anion channel in a Plasmodium falciparum genetic cross.

  Human erythrocytes infected with the malaria parasite Plasmodium falciparum have increased permeabilities to many solutes. The plasmodial surface anio…

  Authors: Abdulnaser Alkhalil, Ajay D Pillai, Abdullah A B Bokhari, Akhil B Vaidya, Sanjay A Desai

  Source: Molecular microbiology. 2009 Apr

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• Mitochondria in malaria and related parasites: ancient, diverse and streamlined.

  Parasitic organisms have emerged from nearly every corner of the eukaryotic kingdom and hence display tremendous diversity of form and function. This …

  Authors: Michael W Mather, Akhil B Vaidya

  Source: Journal of bioenergetics and biomembranes. 2008 Oct

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• Mitochondrial drug targets in apicomplexan parasites.

  In evolutionary terms, mitochondria in apicomplexan parasites appear to be "relicts-in-the-making": they possess the smallest mitochondrial genomes kn…

  Authors: Michael W Mather, Karl W Henry, Akhil B Vaidya

  Source: Current drug targets. 2007 Jan

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• Genome sequence of the human malaria parasite Plasmodium falciparum.

  The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million African children annua…

  Authors: Malcolm J Gardner, Neil Hall, Eula Fung, Owen White, Matthew Berriman, Richard W Hyman, Jane M Carlton, Arnab Pain, Karen E Nelson, Sharen Bowman,…

  Source: Nature. 2002 Oct 3

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• Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii.

  Species of malaria parasite that infect rodents have long been used as models for malaria disease research. Here we report the whole-genome shotgun se…

  Authors: Jane M Carlton, Samuel V Angiuoli, Bernard B Suh, Taco W Kooij, Mihaela Pertea, Joana C Silva, Maria D Ermolaeva, Jonathan E Allen, Jeremy D Selengut, Hean L Koo,…

  Source: Nature. 2002 Oct 3

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• The validity of mitochondrial dehydrogenases as antimalarial drug targets.

  Authors: Akhil B Vaidya, Heather J Painter, Joanne M Morrisey, Michael W Mather

  Source: Trends in parasitology. 2008 Jan

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• Alteration in host cell tropism limits the efficacy of immunization with a surface protein of malaria merozoites.

  Immunization with Plasmodium yoelii merozoite surface protein-8 (PyMSP-8) has been shown to protect mice against lethal P. yoelii 17XL malaria. Here w…

  Authors: Qifang Shi, Amy Cernetich, Thomas M Daly, Gina Galvan, Akhil B Vaidya, Lawrence W Bergman, James M Burns

  Source: Infection and immunity. 2005 Oct

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• A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites.

  Pore-forming proteins are employed by many pathogens to achieve successful host colonization. Intracellular pathogens use pore-forming proteins to inv…

  Authors: Karine Kaiser, Nelly Camargo, Isabelle Coppens, Joanne M Morrisey, Akhil B Vaidya, Stefan H I Kappe

  Source: Molecular and biochemical parasitology. 2004 Jan

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