1 to 9 of 9 literature results

• Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels.

  The survival of T lymphocytes requires sustained, Ca(2+) influx-dependent gene expression. The molecular mechanism that governs sustained Ca(2+) influ…

  Authors: Mithilesh K Jha, Abdallah Badou, Marcel Meissner, John E McRory, Marc Freichel, Veit Flockerzi, Richard A Flavell

  Source: Nature immunology. 2009 Dec

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• A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.

  Engagement of the T cell antigen receptor (TCR) during antigen presentation initiates a coordinated action of a large number of signaling proteins and…

  Authors: Didi Matza, Abdallah Badou, Koichi S Kobayashi, Karen Goldsmith-Pestana, Yutaka Masuda, Akihiko Komuro, Diane McMahon-Pratt, Vincent T Marchesi, Richard A Flavell

  Source: Immunity. 2008 Jan

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• Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.

  In this study we investigated the signaling pathways triggered by Tat in human monocyte to induce TNF-alpha. In monocytes, the calcium, the PKA, and t…

  Authors: Yamina Bennasser, Abdallah Badou, Jean Tkaczuk, Elmostafa Bahraoui

  Source: Virology. 2002 Nov 10

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• Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.

  Cytolytic CD8(+) T cells (CTLs) kill virally infected cells, tumor cells, or other potentially autoreactive T cells in a calcium-dependent manner. To …

  Authors: Didi Matza, Abdallah Badou, Mithilesh K Jha, Tim Willinger, Andrey Antov, Shomyseh Sanjabi, Koichi S Kobayashi, Vincent T Marchesi, Richard A Flavell

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Jun 16

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• Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9.

  Apoptosis of hepatocytes results in the development of liver fibrosis, but the molecular signals mediating this are poorly understood. Degradation and…

  Authors: Azuma Watanabe, Ardeshir Hashmi, Dawidson Assis Gomes, Terrence Town, Abdallah Badou, Richard Anthony Flavell, Wajahat Zafar Mehal

  Source: Hepatology (Baltimore, Md.). 2007 Nov

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• Critical role for the beta regulatory subunits of Cav channels in T lymphocyte function.

  Calcium ion is a universal signaling intermediate, which is known to control various biological processes. In excitable cells, voltage-gated calcium c…

  Authors: Abdallah Badou, Mithilesh Kumar Jha, Didi Matza, Wajahat Z Mehal, Marc Freichel, Veit Flockerzi, Richard A Flavell

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Oct 17

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• Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions.

  Calcium is known to play vital roles in diverse physiological processes, and it is known that voltage-gated calcium channels (Cav) mediate calcium inf…

  Authors: Abdallah Badou, Srisaila Basavappa, Rooma Desai, You-Qing Peng, Didi Matza, Wajahat Z Mehal, Leonard K Kaczmarek, Emile L Boulpaep, Richard A Flavell

  Source: Science (New York, N.Y.). 2005 Jan 7

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• Activation of CD4 T cells by Raf-independent effectors of Ras.

  Small GTPase Ras is capable of mediating activation in T lymphocytes by using Raf kinase-dependent signaling pathway. Other effectors of Ras exist, ho…

  Authors: Jan Czyzyk, Jennifer L Brogdon, Abdallah Badou, Octavian Henegariu, Paula Preston Hurlburt, Richard Flavell, Kim Bottomly

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2003 May 13

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• Retraction.

  Authors: Richard A Flavell, Leonard K Kaczmarek, Abdallah Badou, Emile L Boulpaep, Rooma Desai, Srisaila Basavappa, Didi Matza, You-Qing Peng, Wajahat Z Mehal

  Source: Science (New York, N.Y.). 2005 Dec 23

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