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Two new diterpenoids, named isodoternifolin A and B, together with seven known compounds were isolated from the ethanol extract of dried stems and leaves of Isodon ternifolius (D. Don) Kudo. Their structures were determined as 7 beta-hydroxy-6 beta, 11 alpha, 15 beta-triacetoxy-7 alpha, 20-epoxyentkaur-16-ene (1) and 6 beta, 7 beta, 15 beta-trihydroxy-11 alpha-acetoxy-7 alpha, 20-epoxy-entkaur-16-ene (2) by chemical and spectral evidence.


Z M Wang, H Feng, X T Liang, S T Yuan, M J Xu. New diterpenoids, isodoternifolins A and B, from Isodon ternifolius]. Yao xue xue bao = Acta pharmaceutica Sinica. 1996;31(10):764-9

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PMID: 9863245

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