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A novel sesquiterpene, 7 alpha-hydroxy-6, 11-cyclofarnes-3(15)-en-2-one [1], has been isolated from the aerial parts of Premna oligotricha (Verbenaceae) using an antimicrobial bioassay-guided isolation procedure. The sesquiterpene was identified on the basis of spectroscopic data and showed weak activity against Gram-positive bacteria Bacillus pumilus, Bacillus subtilis, Staphylococcus aureus, and Streptococcus faecalis.


S Habtemariam, A I Gray, P G Waterman. A new antibacterial sesquiterpene from Premna oligotricha. Journal of natural products. 1993 Jan;56(1):140-3

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PMID: 8450316

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