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The venomous spines of P. volitans contain a non-proteinaceous ichthyotoxin of low molecular weight. This toxin could be isolated only from spines excised from the living fish; the toxin is apparently destroyed following death, as the extracts of the spines of the dead fish were non-toxic.

Citation

M S Nair, P Cheung, I Leong, G D Ruggieri. A non-proteinaceous toxin from the venomous spines of the lionfish Pterois volitans (Linnaeus). Toxicon : official journal of the International Society on Toxinology. 1985;23(3):525-7

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PMID: 4024148

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