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Antithrombotic medications have become standard of care for management of acute coronary syndrome. Platelet adhesion, activation, and aggregation are essential components of platelet function; platelet-inhibiting medications interfere with these components and reduce incidence of thrombosis. Active bleeding is a contraindication for administration of platelet inhibitors. There is currently no reversal agent for platelet inhibitors, although platelet transfusion may be used to correct active bleeding after administration of platelet inhibitors. Copyright © 2016 Elsevier Inc. All rights reserved.


Megan M Shifrin, S Brian Widmar. Platelet Inhibitors. The Nursing clinics of North America. 2016 Mar;51(1):29-43

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PMID: 26897422

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