Clear Search sequence regions


  • adult (1)
  • carotid body (6)
  • cell numbers (1)
  • cells (2)
  • cells glial (1)
  • cells human (1)
  • galanin (5)
  • growth (1)
  • homeostasis (1)
  • human (3)
  • hypoxia (1)
  • oxygen (1)
  • signals (1)
  • Sizes of these terms reflect their relevance to your search.

    The carotid body is a neural-crest-derived organ devoted to respiratory homeostasis through sensing changes in blood oxygen levels. The sensory units are the glomeruli composed of clusters of neuronal-like (type I) cells surrounded by glial-like (type II) cells. During chronic hypoxia, the carotid body shows growth, with increasing neuronal-like cell numbers. We are interested in the signals involved in the mechanisms that underlie such response, because they are not well understood and described. Considering that, in literature, galanin is involved in neurotrophic or neuroprotective role in cell proliferation and is expressed in animal carotid body, we investigated its expression in human. Here, we have shown the expression and localisation of galanin in the human carotid body.

    Citation

    Camillo Di Giulio, Guya Diletta Marconi, Susi Zara, Andrea Di Tano, Andrea Porzionato, Mieczyslaw Pokorski, Amelia Cataldi, Andrea Mazzatenta. Selective Expression of Galanin in Neuronal-Like Cells of the Human Carotid Body. Advances in experimental medicine and biology. 2015;860:315-23

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 26303496

    View Full Text