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A new coumarin, edgeworic acid (1), was isolated from the flower buds of Edgeworthia chrysantha, together with the five known coumarins umbelliferone (2), 5,7-dimethoxycoumarin (3), daphnoretin (4), edgeworoside C (5), and edgeworoside A (6). Their structures were established on the basis of spectral data, particularly by the use of 1D NMR and several 2D shift-correlated NMR pulse sequences (1H-1H COSY, HSQC and HMBC), in combination with acetylation reactions.


Xing-Nuo Li, Sheng-Qiang Tong, Dong-Ping Cheng, Qing-Yong Li, Ji-Zhong Yan. Coumarins from Edgeworthia chrysantha. Molecules (Basel, Switzerland). 2014;19(2):2042-8

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PMID: 24531219

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