Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

Treg cells expressing the Foxp3 transcription factor play a key role in several aspects of immunological tolerance and in the establishment of immune homeostasis. Here, we discuss the mechanisms, including new evidence on the signals required by Tconv cells to convert into Treg cells described by Yao and colleagues [Eur. J. Immunol. 2013. 43: 458-467] in this issue of European Journal of Immunology, by which Treg-cell dynamics, plasticity and diversification correlate with diverse functions (induction, suppression, contra-suppression) in a variety of settings, such as inflammation, chronic infections, cancer, and autoimmunity. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Citation

Vincenzo Barnaba, Valeria Schinzari. Induction, control, and plasticity of Treg cells: the immune regulatory network revised? European journal of immunology. 2013 Feb;43(2):318-22

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 23408318

View Full Text