Clear Search sequence regions

This longitudinal study examines the association between homelessness and injection drug use initiation among a cohort of street-involved youth in a setting of high-prevalence crystal methamphetamine use. We derived data from the At-Risk Youth Study, a prospective cohort of street-involved youth aged 14-26 years, recruited between September 2005 and November 2011. We used Cox proportional hazards regression to identify factors independently associated with time to injection initiation. Among 422 street-youth who had never injected at baseline, we observed 77 injection initiation events during follow-up. Homelessness was independently associated with injection initiation in multivariate Cox regression (relative hazard, 1.80 [95% confidence interval, 1.13-2.87]) after adjusting for crystal methamphetamine use and other potential confounders. These findings highlight that homelessness is a key risk factor for injection initiation among street-involved youth. Supportive housing interventions for street youth may help prevent injection drug use initiation within this high-risk population. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.


Cindy Feng, Kora DeBeck, Thomas Kerr, Steve Mathias, Julio Montaner, Evan Wood. Homelessness independently predicts injection drug use initiation among street-involved youth in a Canadian setting. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. 2013 Apr;52(4):499-501

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 23299006

View Full Text