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A 70-year-old woman was referred to our hospital because of abdominal pain. Abdominal computed tomography(CT)and colonoscopy revealed transverse colon cancer with multiple liver metastases, with involvement of the hepatic pedicle and superior mesenteric artery lymph nodes. The patient received eight courses of XELOX plus bevacizumab, and CT showed a decrease in the size of the liver metastases and hepatic pedicle lymphadenopathy. Right hemicolectomy, partial hepatectomy, and hepatic pedicle lymph node resection were performed. Histopathological examination of the resected tissue revealed no residual cancer cells, suggesting a pathological complete response. The patient remains well 7 months after operation, without any signs of recurrence. Surgical resection should be considered for patients with initially unresectable colon cancer with liver metastases and hepatic pedicle lymph nodes involvement if systemic chemotherapy is effective.

Citation

Toshiki Mukai, Takashi Akiyoshi, Rintaro Koga, Junichi Arita, Akio Saiura, Atsushi Ikeda, Yasutomo Nagasue, Yoshinori Oikawa, Keiko Yamakawa, Tsuyoshi Konishi, Yoshiya Fujimoto, Satoshi Nagayama, Yosuke Fukunaga, Masashi Ueno, Mitsukuni Suenaga, Nobuyuki Mizunuma, Eiji Shinozaki, Chiriko Yamamoto, Toshiharu Yamaguchi. A case of transverse colon cancer with multiple liver metastases and hepatic pedicle lymph node involvement showing pathological complete response by XELOX plus bevacizumab]. Gan to kagaku ryoho. Cancer & chemotherapy. 2012 Dec;39(13):2561-3

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PMID: 23235180

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