Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

The antiplatelets drug ticlopidine is widely used in patients suffering from cardiomyopathies, coronary cardiopathies and thromboembolic pathologies. The potential and frequently seen side effects are diarrhoea, hematological dyscrasias and rashes. We describe a case in which the use of ticlopidine in the treatment and prophylaxis of transit ischemic attacks triggered the unusual and rare complication of toxic epidermal necrolysis (TEN). We will then go on to analyse the clinical-pathological aspects and therapies through the use of i.v. immunoglobulins at high dosages that led to a full recovery of the patient.


D Strippoli, G Russo, V Simonetti, A Motolese. Lyell syndrome due to ticlopidine. Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia. 2011 Dec;146(6):497-500

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 22095182

View Full Text