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To study the chemical constituents of Ligusticum sinense. The chemical constituents were isolated and purified by column chromatography on silica gel and Sephadex LH-20; Using spectroscopy methods to elucidate their structures. Nine compounds were isolated and identified as levistolide A (1), (Z)-3-butylidene-7-hydroxyphthalide (2), senkyunolide B (3), 3-butylphthalide(4), (Z)-ligustilide (5), riligustilide (6), neocnidilide (7), senkyunolide A (8), beta-sitostesol (9). Compounds 2 and 3 are obtained from this plant for the first time.


Jia Wang, Jian-Bo Yang, Ai-Guo Wang, Teng-Fei Ji, Ya-Lun Su. Studies on the chemical constituents of Ligusticum sinense]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2011 Mar;34(3):378-80

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PMID: 21823452

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