Products 
Content
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Experimental Data
NextBio's integrated database contains publicly available data from a variety of sources, including GEO, caBIG, and Array Express, among others. All data entering NextBio undergoes a rigorous quality control process and passes through our semi-automated curation and tagging pipeline. All data within NextBio is correlated, and billions of pre-computations are calculated, enabling instant access to all studies and associations. NextBio is current with GEO, containing over 4,000 studies, 30,000 study results, and over 2 billion data points. NextBio's comprehensive database spans many major therapeutic groups and disease states.
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Literature, News, and Clinical Trials
Using our ontological framework, NextBio searches across text-based resources, such a literature, news, and clinical trials, to find all relevant information related to each search. NextBio contains over 18 million citations with full abstracts including all full-text content available in PubMed Central, over 56,000 clinical trials listings, and aggregated science news pulled from hundreds of sources.
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Biogroups
Biogroups are collections of genes sharing a specific biological function or pathway. Biogroups consist of signaling and metabolic pathways, protein families, gene ontologies, as well as other relevant gene sets. Examples of canonical gene lists represented as biogroups include those from the Gene Ontology Consortium and the Broad Institute's MSigDB. NextBio's library contains over 34,000 biogroups.
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Ontologies
With NextBio, all synonyms for genes, diseases, or drugs are recognized, allowing all relevant information to be presented for each and every query. NextBio incorporates sets of ontologies that include 65,000 disease concepts, 8 million compound clusters, and thousands of tissues, among others.
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Cross-species Search
Currently, NextBio supports 6 model organisms. Based on our ontologies, NextBio has created a cross-species ortholog-based translation engine, enabling users to retrieve all relevant results for genes, regardless of organism. This provides the largest possible context to interpret gene function and activity in normal tissues or disease states.
